The Anti-TRMT61B Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-TRMT61B Antibody, Rabbit Polyclonal has been validated for the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
TRMT61B (TRNA Methyltransferase 61B) is a Protein Coding gene. The TRMT61B gene, located on 2p23.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, chicken, zebrafish, and frog. TRMT61B is a methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in the mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC). TRMT61B catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosome structure and function. TRMT61B is widely expressed in the testis, small intestine, and other tissues. Diseases associated with TRMT61B include Codas Syndrome and Combined Oxidative Phosphorylation Deficiency 30